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Martha’s Better Ewing Sarcoma Treatment (BEST) Grant for All

Grants to USA, Canada, and International Researchers
and Teams to Support Research Related to Cures for Ewing Sarcoma

Agency Type:

Foundation / Corporation

Funding Source:

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St. Baldrick’s Foundation

LOI Date:


Deadline Date:

08/30/19 5:00 PM EST


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Grants to USA, Canada, and International individual researchers and teams to support efforts to find treatments for Ewing Sarcoma. Applicants must submit an LOI prior to submitting a full application. Funding is intended to support proposals that examine innovative concepts with the potential for high impact and quick movement to improvements in outcomes for patients.

Requirements and Considerations:
- Applications with the potential to lead to clinical trials within three years will be prioritized
- Projects involving gene therapy, immunotherapy or the use of novel techniques like CRISPR will be well received.
- If basic science, applications must have the potential for game-changing results.
- Proposals without clear path to the therapeutic interventions will receive a low priority.
- Both hypothesis-driven and hypothesis-neutral (e.g., drug screening and genome-wide molecular characterization) approaches will be considered, as long as the outcome of the project leads to actionable therapeutic intervention within the suggested time frame.
- Cross discipline collaboration is encouraged, with each investigator’s role and responsibility clearly outlined in the proposal.
- Applications must include proposed timeline with anticipated milestones.
- The Principal Investigator will report progress in person or by videoconference every six months and will submit a written report of progress annually.

Applications that are innovative, risk-taking, and use novel tools and methods will be prioritized. Applications may be from individuals or teams, with collaboration highly valued.

GrantWatch ID#:

GrantWatch ID#: 186175

Estimated Size of Grant:

The award will total $325,000/year for 3 years, distributed annually. Funding starting from the 2nd installment will be evaluated based on research progress.

Term of Contract:

This is a three-year award.

Additional Eligibility Criteria:

- Applications will be accepted from both individual researchers and teams, with collaborative approaches preferred.
- Applications will be accepted from any country.
- An institution may submit more than one application for this RFA.
- A researcher can only apply once as the lead Principal Investigator.
- Applicants should hold at least a M.D., D.O., Ph.D., or international equivalent degree by the date the award becomes effective

The Foundation does not provide funds for items such as:
- Secretarial/administrative salaries.
- Student tuition (tuition is allowable for International Scholar awards).
- Office and laboratory furniture.
- Office equipment and supplies.
- Recruiting and relocation expenses.
- Non-medical services to patients (travel to a clinical site or patient incentives are allowable expenses).
- Construction, renovation, or maintenance of buildings/laboratories.
- Professional association membership dues.
- Scientific publication subscriptions.

St. Baldrick’s funds may not be used for human embryonic stem cell research.

Pre-Application Information:

Key Dates:

Letter of Intent (LOI), application and required documents must be submitted by the Principal Investigator, in English, online before 5 p.m. EASTERN TIME on the deadline.

- Letter of intent due: 07/12/2019 before 5pm EASTERN TIME
- Letter of intent approval: 08/1/2019
- Full proposal due: 08/30/2019 before 5pm EASTERN TIME
- Notification of award: November
- Project start date: 1/1/2020

St. Baldrick’s Foundation funds biomedical research to better understand the causes of pediatric cancers and to advance its prevention, treatment, and cure. The main output of this research is new knowledge. To ensure this knowledge can be accessed, read, applied, and built upon in fulfillment of the Foundation goals, St. Baldrick’s Foundation encourages researchers to share data with the research community in accordance with the NIH policy on data sharing and expects its grantees to publish their findings, including but not limited to publication in peer reviewed journals. Applicants will be asked to provide data sharing plans as part of the application.

Contact Information:

Before starting your grant application, please review the funding source's website listed below for updates/changes/addendums/conferences/LOIs.

To submit an LOI:

For grant inquiries:
St. Baldrick’s Foundation
Department of Grants Administration
(626) 792-8247, extension 236

For help using the online application system:
ProposalCENTRAL Customer Support
(800) 875-2562

St. Baldrick’s Foundation
1333 South Mayflower Avenue, Suite 400
Monrovia, CA 91016 USA

URL for Full Text (RFP):

Geographic Focus:

USA: Alabama;   Alaska;   Arizona;   Arkansas;   California;   Colorado;   Connecticut;   Delaware;   Florida;   Georgia;   Hawaii;   Idaho;   Illinois;   Indiana;   Iowa;   Kansas;   Kentucky;   Louisiana;   Maine;   Maryland;   Massachusetts;   Michigan;   Minnesota;   Mississippi;   Missouri;   Montana;   Nebraska;   Nevada;   New Hampshire;   New Jersey;   New Mexico;   New York City;   New York;   North Carolina;   North Dakota;   Ohio;   Oklahoma;   Oregon;   Pennsylvania;   Rhode Island;   South Carolina;   South Dakota;   Tennessee;   Texas;   Utah;   Vermont;   Virginia;   Washington, DC;   Washington;   West Virginia;   Wisconsin;   Wyoming

USA Territories: American Samoa (USA)   Guam (USA)   Puerto Rico (USA)   Virgin Islands (USA)   Northern Mariana Islands (USA)

USA Compact Free Associations: The Federated States of Micronesia (USA)   Marshall Islands (USA)   Republic of Palau (USA)

Canada: Alberta   British Columbia   Manitoba   New Brunswick   Newfoundland and Labrador   Northwest Territories   Nova Scotia   Nunavut   Ontario   Prince Edward Island   Quebec   Saskatchewan   Yukon


International country outside of the USA, Israel and Canada.

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